In order to improve the service performance and increase the performance richness of the engine rotating disc, the forming process, microstructure and mechanical properties of TC17 titanium alloy disc forging of the original process for an engine were analyzed. It was found that the preforming design of the original process was unreasonable, which led to the uneven distribution of the equivalent strain and microstructure of the disc forging. The ductility and low cycle fatigue properties of disc forgings were low. To solve this problem, finite element simulation was used to optimize the preforming structure, and the deformation uniformity and microstructure performance of disk forgings were further improved. After optimization, the uneven deformation of forgings is obviously improved, and the microstructure distribution of each part of the forgings is uniform and the morphology characteristics are better. The morphology characteristics are the elongated β grains, and there is no or few β recrystallized grains, grain boundary bending, basketwaved structure inside grain. The results show that the ductility and low cycle fatigue properties of the disk forging of the optimized process are better than those of the original process, and the mechanical properties of each part of the optimized disc forgings have less dispersion and better stability.