Diesel vehicle exhaust is one of the main sources of nitrogen oxides (NOx) in the atmosphere, and selective catalytic reduction of NH3 (NH3-SCR) is the most mature technical means to remove NOx from mobile sources. In the past decade, metal-based molecular sieve catalysts have become the focus of NOx removal catalysts in diesel vehicle exhaust due to their advantages of wider activity temperature window and better thermal stability, among which, Cubased small-pore molecular sieve catalysts have already been commercially applied. However, the increasingly stringent NOx emission standards have put forward higher requirements on the performance of denitrification catalysts in terms of low-temperature activity, hydrothermal stability, and resistance to toxicity. Therefore, many scholars have conducted more in-depth research on the catalytic mechanism and improvement strategy of molecular sieve catalysts, and good progress has been achieved. In this paper, the research progress of molecular sieve NH3-SCR catalysts is reviewed from the aspects of reaction mechanism, low-temperature activity, hydrothermal stability,poisoning and anti-poisoning strategy, and its application prospect is prospected, aiming to provide theoretical guidance for the development of high-performance molecular sieve denitrification catalysts.