On the basis of earlier test results, TC4 industrial ingot was prepared using electron beam cold hearth single melting. The multiplepoint element analysis showed the composition uniformity of TC4 alloy met the demand of national standard, indicating that the domestic technology of controlling TC4 element volatilization and alloying during EB melting process had become mature, which enables us to possibly fabricate TC4 alloy via onestep. Using this TC4 ingot, the experiments of various working modes and deformation amounts were carried out. The results indicated that the deformation mode and deformation amount produced obvious effect on the TC4 ingot’s microstructure, but little effect on properties, and properties with different microstructure showed little difference during processing primary stages and mid stages. As the processing continued, the microstructure difference of the samples decreased but the property difference increased. This tendency is different from the conventional TC4 alloy using consumable electrode vacuum furnace, which may result from its melting method. Further research should be widely carried out.