（1. College of Metallurgical Engineering, Xi’an University of Architecture and Technology, Xi’an 710055, China) (2 National Experimental Teaching Demonstration Center of Metallurgical Techniques, Xi’an University of Architecture and Technology, Xi’an 710055, China)
With the rapid increase of biomedical metal materials in the market, biomedical titanium and titanium alloys have become the main raw materials for human implants. However, the performance of conventional titanium and titanium alloys compared with stainless steel and diamond-based alloys in various aspects in the medical field is excellent, but its performance as an implant in the more complex environment of the human body needs to be improved. Therefore, the research and development of ultrafine-grained titanium and titanium alloys have great practical significance and broad market prospects in the medical market. At present, the preparation of ultrafine-grained metal materials on the market is mainly based on the severe plastic deformation process, and the equal channel angular pressing deformation method is more mature. This article briefly introduces the types and characteristics of biomedical ultrafine-grain titanium and titanium alloys, focusing on the biomedical corrosion resistance, biocompatibility, mechanical property and fatigue performance of ultrafine-grained titanium and titanium alloys prepared from equal channel angular pressing deformation method. Meanwhile the future development trend of biomedical ultrafine-grain titanium and titanium alloy in the medical market, and the problems to be solved are introduced.