Due to their high theoretical energy density, lithium-sulfur batteries have become the research hotspot in the field of high-performance rechargeable batteries in recent years. In order to effectively improve the electrochemical performance of lithium-sulfur batteries, metal-organic frameworks (MOFs) with controllable pore size distribution, ultrahigh porosity and easy functionalization ability have been extensively explored and studied. By modifying MOFs, various MOF composites and MOF derivatives have showed better electrochemical performance, which effectively improve reaction kinetics of electrodes and cycling performance of batteries. In this paper, research progresses of various MOFs, MOF composites and MOF derivatives in cathode of lithium-sulfur batteries were reviewed based on the key issues in the current research of lithium-sulfur batteries, and the future development trends of MOF-based materials-application in cathode of lithium-sulfur batteries were put forward.