[1]王颖,何晋,刘茜,等.中枢神经系统损伤修复生物材料研究进展[J].中国材料进展,2012,(5):011-19.[doi:10.7502/j.issn.1674-3962.2012.05.02]
WANG Ying,HE Jin,LIU Xi,et al.Research Progress on Biomaterials for Treatment of Central Nervous System Injuries[J].MATERIALS CHINA,2012,(5):011-19.[doi:10.7502/j.issn.1674-3962.2012.05.02]
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中枢神经系统损伤修复生物材料研究进展(
)
中国材料进展[ISSN:1674-3962/CN:61-1473/TG]
- 卷:
-
- 期数:
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2012年第5期
- 页码:
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011-19
- 栏目:
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特约研究论文
- 出版日期:
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2012-05-25
文章信息/Info
- Title:
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Research Progress on Biomaterials for Treatment of Central Nervous System Injuries
- 作者:
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王颖; 何晋; 刘茜; 郭牧遥; 王秀梅; 崔福斋
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(清华大学材料科学与工程系 再生医学与仿生材料研究所，北京 100084)
- Author(s):
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WANG Ying; HE Jin; LIU Xi; GUO Muyao; WANG Xiumei; CUI Fuzhai
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(Institute for Regenerative Medicine and Biomimetic Materials, Department of Materials Science and Engineering, Tsinghua University, Beijing 100084, China)
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- 关键词:
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中枢神经系统; 组织工程; 纳米生物材料
- DOI:
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10.7502/j.issn.1674-3962.2012.05.02
- 文献标志码:
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A
- 摘要:
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中枢神经系统损伤导致神经细胞死亡、组织破坏，造成神经功能永久性缺失，是长期困扰生物医学界的一大难题，目前尚无有效疗法。组织工程技术不仅能通过纳米生物材料为神经细胞和神经纤维生长提供结构支持，还能同时递送各种有利于神经再生修复的活性信号分子，有望在促进中枢神经损伤组织修复的同时，实现神经功能的重建，为中枢神经损伤再生修复带来希望。结合国内外有关中枢神经系统组织工程研究的最新进展，对中枢神经修复生物材料设计的主要策略、以及包括天然生物大分子和合成高分子在内的多种中枢神经修复生物材料的应用进行了详细综述。
- Abstract:
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Injuries to central nervous system (CNS) lead to severe and permanent neurological deficits. Tissue engineering is the most hopeful treatment by providing a regenerative environment in the CNS after injury as well as delivering cells to the injured site. Artificial scaffolds not only provide a suitable support for axonal regeneration and cellular migration, but delivery many bioactive molecules for neural repair. In this review we discuss the development of scaffolds and current strategies for designing scaffolds for CNS tissue engineering.
更新日期/Last Update:
2012-07-19