生物3D打印高分子材料发展现状与趋势-中国材料进展

文章信息/Info

Author(s):: MAO Hongli; GU Zhongwei; College of Materials Science and Engineering, Nanjing Tech University

Keywords:: 3D bioprinting; biomaterials; synthetic polymer; natural polymer; decellularizate ECM

摘要:: 生物3D打印作为3D打印的一个重要分支，在健康医疗领域表现出巨大的应用价值。材料则是目前该领域的研究热点，更是关乎其深入发展和实际应用的关键因素。其中，高分子材料在生物3D打印，尤其是载细胞打印中，可谓异军突起，成为发展最快的一类打印材料。鉴于此，本文在简要介绍生物3D打印技术及相关原理的基础上，对生物3D打印在健康医疗领域的应用进行了分类叙述。同时，综述了生物3D打印对材料的特性要求，并重点针对生物3D打印高分子材料，详细介绍了典型合成高分子及天然高分子在生物3D打印中的最新研究进展。最后对高分子材料在生物3D打印中未来发展趋势和研究方向提出展望。

Abstract:: As an important branch of 3D printing, 3D bioprinting showed great petential in the field of health care. Printing materials are currently the research hotspots in this field, and they are also the key factors for the further development and application of 3D bioprinting. Materials currently used in the field of 3D bioprinting are predominantly based on either synthetic molecules or naturally derived polymers. In view of this, this paper introduced the technology and principles in 3D bioprinting firstly, and then described the application of 3D bioprinting in the field of health care. Meanwhile, the requirements on bioprinting materials were reviewed, and the recent progress of typical synthetic polymers and natural polymers used in 3D bioprinting was introduced in detail. Finally, the future development trend and research direction of polymer materials in 3D bioprinting were proposed.