(Institute for Regenerative Medicine and Biomimetic Materials, Department of Materials Science and Engineering, Tsinghua University, Beijing 100084, China)
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DOI:
10.7502/j.issn.1674-3962.2012.05.02
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Abstract:
Injuries to central nervous system (CNS) lead to severe and permanent neurological deficits. Tissue engineering is the most hopeful treatment by providing a regenerative environment in the CNS after injury as well as delivering cells to the injured site. Artificial scaffolds not only provide a suitable support for axonal regeneration and cellular migration, but delivery many bioactive molecules for neural repair. In this review we discuss the development of scaffolds and current strategies for designing scaffolds for CNS tissue engineering.