Abstract

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Author(s):: ZHENG Jiaoni1; LIAO Rongqiang1; 2; YANG Bo2; 1. Chongqing Emergency Medical Center, Chongqing University Center Hospital,Department of Pharmacy, Chongqing Fourth Peoples Hospital, Chongqing 400014, China
2. Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China

Abstract:: With the development of nanomedicine and precision medicine, the potential application of nanodrugs and gene delivery system is gradually manifested in the field of cancer treatment. Nano technology can not only improve the bioavailability but also reduce the toxicity, which is of great significance for developing new drugs. Selfassembly supramolecular technology has been one of the hottest topics in nano biotechnology for a long time. We can take advantage of the noncovalent bond selfassembly technology to construct supramolecular assemblies with their novel structures and functions, which is of great significance for nanodrug and gene carrier. Cyclodextrins are widely used in the construction of nanodrug and gene carrier ascribing to their virtues of ready availability, low toxicity, selfassembly, and functional flexibility. This paper mainly introduces the nanodrug and gene carrier based on cyclodextrin, some personal perspectives on this field are also presented.