可降解材料在骨科临床中的应用-中国材料进展

文章信息/Info

Author(s):: SHEN Yongshuai; LIU Xinchun; The First Hospital of China Medical University

摘要:: 骨科使用的不可吸收材料基本满足临床应用需求，但随着骨科技术的不断发展，临床上对于骨科材料的性能有了更高的要求。可降解材料具有优秀的力学性能和生物学性能，已逐渐成为骨科材料研究的热点。目前，骨科应用可降解材料种类繁多，主要包括四大类：可降解医用金属材料、可降解高分子材料、无机材料和复合材料。可降解医用金属材料是理想的内固定材料，可降解高分子材料和无机材料多用于缝线、填充和支架材料，而复合材料具备其他三种材料不同的优点，是未来研究的重点。通过广泛查阅国内外近几年有关可降解材料的研究报告，从上述四大分类综述了可降解材料的研究进展及待解决问题，并且对可降解材料的发展做出了展望。

Abstract:: Non-biodegradable materials can basically meet the demand of clinical orthopaedics application. But, with the development of orthopedics technology, there is a higher demand for orthopedics material performance in the clinical. Biodegradable materials gradually become one of research focuses in the clinical orthopaedics, because of their excellent mechanical properties and biological properties.Recently, there are a wide variety of degradable orthopedics materials, which can be mainly divided into four categories: degradable medical metal materials, degradable polymer materials, inorganic materials and composite materials. Biodegradable medical metal material is an ideal internal fixation material. Biodegradable polymer materials and inorganic materials are used for stitching, filling and scaffold materials. Composite material has the advantages of other three materials, which is the focus of future research. By consulting a large number of overseas and domestic research reports in recent years, new progress and problems demanding prompt solution in biodegradable materials are summarized, through the above four categories. In addition, the trends of their development are discussed.