新型抗菌功能医用金属研究-中国材料进展

文章信息/Info

作者:: 杨柯; 任玲; 张余; 马政; 张丹; 梅晰凡; (1.中国科学院金属研究所，辽宁沈阳 110016) (2.广州军区广州总医院，广东广州 510010) (3.中国医科大学口腔医学院，辽宁沈阳 110001) (4.辽宁医学院，辽宁锦州 121000)

Author(s):: YANG Ke; REN Ling; ZHANG Yu; MA Zheng; ZHANG Dan; MEI Xifan; (1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016,China） (2. Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China) (3. School of Stomatology, China Medical University, Shenyang 110002, China) (4. Liaoning Medical University, Jinzhou 121000, China)

摘要:: 不锈钢、钛及钛合金等医用金属材料已广泛应用于骨科、齿科及心血管介入等医疗领域，生物可降解镁合金是正在研究发展的新型医用金属材料，具有诱人的临床应用前景。面对目前临床上亟待解决的植入物引发的细菌感染问题，开展医用金属材料的抗菌功能研究意义重大，也是实现金属材料结构/功能一体化发展的新探索。简要介绍了作者近年来在不锈钢、钛合金、可降解镁基金属等医用金属材料的抗菌功能研究方面的主要进展，并展望了抗菌医用金属材料的临床应用前景。

Abstract:: Metallic biomaterials such as stainless steels and titanium alloys are widely used in medical areas including orthopedics, dentistry and coronary stents. Biodegradable magnesium alloys are a new class of metallic biomaterials that are being studied and developed with attractive future of clinical applications. In order to solve the currently existed bacterial infections caused by implants, it is great significance to study and develop novel metallic biomaterials with antibacterial functions, which is also a new exploration to realize the structural/functional integrity for metallic materials. This paper briefly introduces the recent research progresses on antibacterial functions of stainless steels, titanium alloys and biodegradable magnesiumbased materials, and proposes the future applications for antibacterial metallic biomaterials.